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NFIB NF1B2 [1H5]

Product code: EM1701-69


  • Overview

  • Product name NFIB NF1B2
  • Molecular Wt 47 kDa
  • Description NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,IHC,FC
  • Antibody type Mouse Monoclonal Antibody
  • Immunogen Recombinant full length protein corresponding to human NFIB/NF1B2.
  • Positive control SH-SY5Y, rat heart tissue, human pancreas tissue, mouse liver tissue.
  • Conjugate Non-conjugated
  • Clone number 1H5
  • Alternative names CCAAT Box Binding Transcription Factor antibody
    CCAAT-box-binding transcription factor antibody
    CTF antibody
    HMGIC/NFIB antibody
    NF-I/B antibody
    NF1-B antibody
    NF1B antibody
    NF1B2 antibody
    NFI-B antibody
    NFI-RED antibody
    Nfib antibody
    NFIB_HUMAN antibody
    NFIB2 antibody
    NFIB3 antibody
    Nuclear factor 1 B-type antibody
    Nuclear factor 1/B antibody
    Nuclear Factor 1B antibody
    Nuclear Factor I B antibody
    Nuclear factor I/B antibody
    TGGCA Binding Protein antibody
    TGGCA-binding protein antibody
    TRANSCRIPTION FACTOR NFIB antibody
  • Properties

  • Form Liquid
  • Concentration 2 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG2b
  • Purity ProG affinity purified.
  • Subcellular location Nucleus.
  • Database links O00712(Human)
    P97863(Mouse)
  • Applications

    WB: 1:500-1:1,000
    IHC: 1:50-1:200
    FC: 1:50-1:100

  • Publishing research using NFIB NF1B2? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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