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GABA A Receptor alpha 5 [JB34-19]

Product code: ET7107-08


  • Overview

  • Product name GABA A Receptor alpha 5
  • Molecular Wt 52 kDa
  • Description GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,ICC,IF,IHC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen Recombinant protein
  • Positive control 293T, A549, SH-SY-5Y, rat brain tissue, mouse brain tissue.
  • Conjugate Non-conjugated
  • Clone number JB34-19
  • Alternative names GAA 5 antibody
    GAA5 antibody
    GABA(A) receptor subunit alpha-5 antibody
    GABRA 5 antibody
    Gabra5 antibody
    Gamma aminobutyric acid GABA A receptor alpha 5 antibody
    Gamma aminobutyric acid GABA A receptor alpha 5 precursor antibody
    Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor antibody
    Gamma-aminobutyric acid receptor subunit alpha-5 antibody
    GBRA5_HUMAN antibody
    GC138184 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Plasma membrane.
  • Database links P31644(Human)
    Q8BHJ7(Mouse)
    P19969(Rat)
  • Applications

    ICC/IF: 1:50-1:200
    IHC: 1:50-1:200
    WB: 1:500

  • Publishing research using GABA A Receptor alpha 5? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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