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Cytochrome P450 Reductase [JB54-31]

Product code: ET7107-35


  • Overview

  • Product name Cytochrome P450 Reductase
  • Molecular Wt 77 kDa
  • Description P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. CYPOR, also known as cytochrome P450 reductase and NADPH cytochrome P450 reductase, is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle. CYPOR is localized to the endoplasmic reticulum, where it is also able to transfer electrons to heme oxygenase and cytochrome b5. CYPOR is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin. Electron transfer of CYPOR requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,ICC,IF,IHC,FC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen Recombinant protein
  • Positive control SK-Br-3, A549, mouse lung tissue lysate, rat brain tissue, human lung cancer tissue, human liver tissue, mouse testis tissue, HepG2.
  • Conjugate Non-conjugated
  • Clone number JB54-31
  • Alternative names CPR antibody
    CYPOR antibody
    Cytochrome p450 oxidoreductase antibody
    DKFZp686G04235 antibody
    FLJ26468 antibody
    NADPH Cytochrome P450 Reductase antibody
    NADPH dependent cytochrome P450 reductase antibody
    NADPHcytochrome P450 reductase antibody
    NCPR_HUMAN antibody
    P450 (cytochrome) oxidoreductase antibody
    P450 Cytochrome Oxidoreductase antibody
    P450R antibody
    por antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Endoplasmic reticulum.
  • Database links P16435(Human)
    P37040(Mouse)
    P00388(Rat)
  • Applications

    WB: 1:500-1:1,000
    ICC: 1:50-1:200
    IHC: 1:50-1:200
    FC: 1:50-1:100

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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