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PBR

Product code: ER1802-11


  • Overview

  • Product name PBR
  • Molecular Wt 10/18 kDa
  • Description Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.
  • Species reactivity Human, Mouse
  • Tested applications WB,IHC
  • Antibody type Rabbit Polyclonal Antibody
  • Immunogen Recombinant protein
  • Positive control A431, PC-3M, human colon cancer tissue, human kidney tissue, mouse colon tissue, mouse brain tissue.
  • Conjugate Non-conjugated
  • Alternative names Benzodiazapine receptor (peripheral) antibody
    Benzodiazepine peripheral binding site antibody
    BPBS antibody
    BZRP antibody
    DBI antibody
    IBP antibody
    Isoquinoline carboxamide-binding protein antibody
    MBR antibody
    mDRC antibody
    Mitochondrial benzodiazepine receptor antibody
    PBR antibody
    PBS antibody
    Peripheral benzodiazepine receptor antibody
    Peripheral benzodiazepine receptor-related protein antibody
    Peripheral type benzodiazepine receptor antibody
    Peripheral-type benzodiazepine receptor antibody
    pk18 antibody
    PKBS antibody
    PTBR antibody
    Ptbzr antibody
    PTBZR02 antibody
    RATPTBZR02 antibody
    translocator protein (18kDa) antibody
    Translocator protein antibody
    Tspo antibody
    Tspo1 antibody
    TSPOA_HUMAN antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Protein affinity purified
  • Subcellular location Mitochondrion.
  • Database links P30536(Human)
    P50637(Mouse)
  • Applications

    WB: 1:500-1:2,000
    IHC: 1:50-1:200

  • Publishing research using PBR? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols
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