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Myosin Light Chain 2

Product code: R1512-19


  • Overview

  • Product name Myosin Light Chain 2
  • Molecular Wt 19 kDa
  • Description Encoded by the MYL2 gene, myosin regulatory light chain 2, ventricular/cardiac muscle isoform, also designated MLC-2 or MLC2v, is part of a hexameric complex of two heavy chains and four light chains predominantly expressed in adult cardiac ventricle muscle. Myosin regulatory light chain 2 binds calcium and has been shown to be a useful molecular marker for cardiac chamber specification. The co-expression of myosin regulatory light chain 7 (MYL7) and myosin regulatory light chain 2 in the outflow tract and atrioventricular canal, together with the single expression in the atrial (MYL7) and ventricular (MYL2) myocardium, permits the delineation of their boundaries. At the amino acid level there is 96% homology between the human and mouse myosin regulatory light chain sequences. Mutations in MYL2 are correlated with mid-left ventricular chamber type hypertrophic cardiomyopathy (MVC2) as well as familial hypertrophic cardiomyopathy type 10 (CMH10).
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,ICC,IHC,FC
  • Antibody type Rabbit Polyclonal Antibody
  • Immunogen Peptide
  • Positive control Mouse skeletal muscle tissue lysate, human skeletal muscle tissue lysate, mouse heart tissue, rat heart tissue, A549, Hela, C2C12.
  • Conjugate Non-conjugated
  • Alternative names Cardiac myosin light chain-2 antibody
    Cardiac ventricular myosin light chain 2 antibody
    CMH10 antibody
    MLC 2v antibody
    MLC-2 antibody
    MLC-2v antibody
    MLC2 antibody
    MLRV_HUMAN antibody
    MYL 2 antibody
    MYL2 antibody
    Myosin light chain 2 regulatory cardiac slow antibody
    Myosin light polypeptide 2 regulatory cardiac slow antibody
    Myosin regulatory light chain 2 antibody
    Myosin regulatory light chain 2 ventricular/cardiac muscle isoform antibody
    Regulatory light chain of myosin antibody
    RLC of myosin antibody
    Slow cardiac myosin regulatory light chain 2 antibody
    ventricular/cardiac muscle isoform antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Peptide affinity purified
  • Subcellular location Cytoplasm.
  • Database links P10916(Human)
    P51667(Mouse)
    P08733(Rat)
  • Applications

    WB: 1:1,000-1:2,000
    ICC: 1:50-1:200
    IHC: 1:50-1:200
    FC: 1:50-1:100

  • Publishing research using Myosin Light Chain 2? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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