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SRY [E9-G4]

Product code: EM1709-61


  • Overview

  • Product name SRY
  • Molecular Wt 40 kDa
  • Description SRY (sex-determining region Y protein) is a tran-scriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.
  • Species reactivity Human
  • Tested applications WB,IHC,FC
  • Antibody type Mouse Monoclonal Antibody
  • Immunogen Recombinant protein
  • Positive control Human SRY recombinant protein, NTERA-2, human cervical cancer tissue, human ovarian cancer tissue, HepG2.
  • Conjugate Non-conjugated
  • Clone number E9-G4
  • Alternative names Essential protein for sex determination in human males antibody
    Sex determining region on Y antibody
    Sex determining region protein antibody
    Sex determining region Y antibody
    Sex-determining region Y protein antibody
    sox21b antibody
    SRXX1 antibody
    SRXY1 antibody
    SRY 1 antibody
    SRY antibody
    SRY_HUMAN antibody
    Sry1 antibody
    Sry3BI antibody
    SRYGENE antibody
    TDF antibody
    TDY antibody
    Testis determining factor antibody
    Testis Determining Factor on Y antibody
    Testis-determining factor antibody
    Transcription factor Sox-21-B antibody
  • Properties

  • Form Liquid
  • Concentration 2 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Isotype IgG1
  • Purity ProA affinity purified
  • Subcellular location Nucleus speckle. Cytoplasm.
  • Database links Q05066(Human)
  • Applications

    WB: 1:500-1:1,000
    IHC: 1:100-1:500
    FC: 1:100-1:200

  • Publishing research using SRY? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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