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TNNI2 [A8-F12]

Product code: EM1709-29


  • Overview

  • Product name TNNI2
  • Molecular Wt 21 kDa
  • Description Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of 2 heavy chains (MHC) and 4 light chains (MLC) that interacts with actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between actin and myosin by binding to calcium. Troponin is made up of at least two subunits, which are skeletal muscle skeletal muscle and slow skeletal muscle. Structures of skeletal muscle troponin are composed of Troponin C (the sensor), Troponin I (the regulator), and Troponin T (the link to the the regulator), and Troponin T C is dumbbell-shaped and has a hydrophobic pocket that increases the contractile force of muscle fibers. Troponin C has 2 isoforms: fast and slow. Fast troponin C has two calci um binding sites while slow / cardiac troponin C has a single calcium binding site.
  • Species reactivity Human
  • Tested applications WB,IHC,FC
  • Antibody type Mouse Monoclonal Antibody
  • Immunogen Recombinant protein
  • Positive control Human TNNI2 recombinant protein, TNNI2-hIgGFc transfected HEK293 cell lysate, human cardiac muscle tissue, human striated muscle tissue, NIH-3T3.
  • Conjugate Non-conjugated
  • Clone number A8-F12
  • Alternative names AMCD 2B antibody
    AMCD2B antibody
    DA 2B antibody
    DA2B antibody
    fast skeletal muscle antibody
    Fast twitch skeletal muscle troponin I antibody
    fast-twitch isoform antibody
    FSSV antibody
    fsTnI antibody
    TNNI 2 antibody
    Tnni2 antibody
    TNNI2_HUMAN antibody
    tro antibody
    Troponin I antibody
    Troponin I fast skeletal muscle antibody
    Troponin I fast twitch 2 antibody
    Troponin I fast twitch isoform antibody
    Troponin I fast twitch skeletal muscle isoform antibody
    Troponin I skeletal fast antibody
    Troponin I type 2 (skeletal fast) antibody
    Troponin I type 2 antibody
  • Properties

  • Form Liquid
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Isotype IgG1
  • Purity ProA affinity purified
  • Subcellular location Nucleus. Cytosol.
  • Database links P48788(Human)
  • Applications

    WB: 1:500-1:1,000
    IHC: 1:100-1:200
    FC: 1:100-1:200

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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