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GPNMB [E5-C10]

Product code: EM1708-60

  • Overview

  • Product name GPNMB
  • Molecular Wt 64 kDa
  • Description Transmembrane glycoprotein NMB (GPNMB), also designated hematopoietic growth factor inducible neurokinin-1 (HGFIN), is a single-pass type I membrane protein. Belonging to the Pmel-17/NMB family of proteins, GPNMB acts as a melanogenic enzyme. GPNMB expression is not restricted to cells of melanocytic lineage and is highest in poorly metastatic melanoma cell lines. There is no expression of GPNMB in highly metastatic melanoma cell lines. GPNMB may play a important role in lymphohematopoietic stem cell maturation.
  • Species reactivity Human
  • Tested applications WB,IHC
  • Antibody type Mouse Monoclonal Antibody
  • Immunogen Recombinant protein
  • Positive control Human GPNMB recombinant protein, GPNMB-hIgGFc transfected HEK293 cell lysate, PANC-1, PC-3 cell lysate, human breast cancer tissue, human esophagus cancer tissue.
  • Conjugate Non-conjugated
  • Clone number E5-C10
  • Alternative names Glycoprotein (transmembrane) nmb antibody
    Glycoprotein nmb antibody
    Glycoprotein nmb like protein antibody
    Gpnmb antibody
    GPNMB_HUMAN antibody
    HGFIN antibody
    NMB antibody
    Osteoactivin antibody
    Transmembrane glycoprotein antibody
    Transmembrane glycoprotein HGFIN antibody
    Transmembrane glycoprotein NMB antibody
  • Properties

  • Form Liquid
  • Concentration 2 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG1
  • Purity ProA affinity purified
  • Subcellular location Membrane. Melanosome.
  • Database links Q14956(Human)
  • Applications

    WB: 1:500
    IHC: 1:100-1:200

  • Publishing research using GPNMB? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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