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Glucose Transporter GLUT3 [JA50-31]

Product code: ET1704-59

  • Overview

  • Product name Glucose Transporter GLUT3
  • Molecular Wt 54 kDa
  • Description Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, Insulin stimulates a rapid and dramatic increase in glucose uptake, largely due to the redistribution of the Insulin-inducible glucose transporter, Glut4. In response to Insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to Insulin. Glut2 expression is seen in pancreatic b cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,IHC,FC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control Human lung tissue lysate, HepG2 cell lysate, mouse heart tissue lysate, human brain tissue, human embryo tissue, mouse brain tissue, SH-SY5Y.
  • Conjugate Non-conjugated
  • Clone number JA50-31
  • Alternative names brain antibody
    FLJ90380 antibody
    Glucose transporter type 3 antibody
    Glucose transporter type 3 brain antibody
    GLUT 3 antibody
    GLUT-3 antibody
    GLUT3 antibody
    GTR3_HUMAN antibody
    Slc2a3 antibody
    Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3 antibody
    Solute carrier family 2, facilitated glucose transporter member 3 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Cell membrane. Multi-pass membrane protein.
  • Database links P11169(Human)
  • Applications

    WB: 1:500-1:2,000
    IHC: 1:50-1:200
    FC: 1:50-1:100

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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