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Clathrin heavy chain [JA53-02]

Product code: ET1704-50


  • Overview

  • Product name Clathrin heavy chain
  • Molecular Wt 191/187 kDa
  • Description Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are englufed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site. The proximal segment of the Clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure.
  • Species reactivity Human, Mouse,Rat
  • Tested applications WB,IHC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control Hela, PC12, human adrenal gland tissue, human colon cancer tissue, human kidney tissue.
  • Conjugate Non-conjugated
  • Clone number JA53-02
  • Alternative names CHC17 antibody
    Clathrin heavy chain antibody
    Clathrin heavy chain 1 antibody
    Clathrin heavy chain 2 antibody
    Clathrin heavy chain like 1 antibody
    Clathrin heavy chain on chromosome 17 antibody
    Clathrin heavy polypeptide antibody
    CLH 17 antibody
    CLH 22 antibody
    CLH-17 antibody
    CLH1_HUMAN antibody
    CLH17 antibody
    CLH22 antibody
    CLTC antibody
    CLTCL antibody
    CLTCL1 antibody
    CLTCL2 antibody
    CLTD antibody
    Hc antibody
    KIAA0034 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Cytoplasmic vesicle membrane.
  • Database links P53675(Human)
    Q68FD5(Mouse)
    P11442(Rat)
  • Applications

    WB: 1:500-1:2,000
    IHC: 1:50-1:200

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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