Clathrin heavy chain
Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are englufed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site. The proximal segment of the Clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure.
Recombinant Rabbit Monoclonal Antibody
Hela, PC12, human adrenal gland tissue, human colon cancer tissue, human kidney tissue.
Clathrin heavy chain antibody
Clathrin heavy chain 1 antibody
Clathrin heavy chain 2 antibody
Clathrin heavy chain like 1 antibody
Clathrin heavy chain on chromosome 17 antibody
Clathrin heavy polypeptide antibody
CLH 17 antibody
CLH 22 antibody
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
ProA affinity purified
Cytoplasmic vesicle membrane.
Fig1: Western blot analysis of Clathrin heavy chain on Hela (1) and PC-12 (2) cell lysate using anti-Clathrin heavy chain antibody at 1/1,000 dilution.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
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