Location: Home >Product >Product Detail

S100 beta [SC57-02]

Product code: ET1610-3


  • Overview

  • Product name S100 beta
  • Molecular Wt 11 kDa
  • Description The family of EF-hand type Ca2+-binding proteins includes calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 α and β, calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins), and the parvalbumin family members, including parvalbumin α and parvalbuminβ(also designated oncomodulin). The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression and differentiation. Research also indicates that the S-100 protein may function in the activation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly and inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100 α chain and S-100 β chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of either two α chains, two β chains or one α and one β chain. S-100 localizes to the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. S-100 is also detected in almost all benign naevi, malignant melanocytic tumours and in Langerhans cells in the skin. Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 α and β are present in a variety of other tissues, and calbindin is present in intestine and kidney.
  • Species reactivity Human, Mouse, Rat, Goat, zebrafish
  • Tested applications WB,ICC/IF,IP,IHC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control N2A, SH-SY-5Y, Hela, HepG2, mouse brain tissue.
  • Conjugate Non-conjugated
  • Clone number SC57-02
  • Alternative names NEF antibody
    Protein S100 B antibody
    Protein S100-B antibody
    S 100 calcium binding protein beta chain antibody
    S 100 protein beta chain antibody
    S-100 protein beta chain antibody
    S-100 protein subunit beta antibody
    S100 antibody
    S100 calcium binding protein beta (neural) antibody
    S100 calcium-binding protein B antibody
    S100 protein beta chain antibody
    S100B antibody
    S100B_HUMAN antibody
    S100beta antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Cytoplasm, Nucleus.
  • Database links P04271(Human)
    P50114(Mouse)
    P04631(Rat)
  • Applications

    WB: 1:1,000-1:5,000
    ICC: 1:50-1:200
    IHC: 1:50-1:200

  • Publishing research using S100 beta? Please let us know so that we can cite the reference in this datasheet.

  • Data sorting...

Choose your product,application and species below,then click "Create".

On the next page you can complete and submit your review.

  • * Code NO.
  • * Application
  • *Sample
  • Species Tested
  • Against
  • Choose text
  • Content

Leave us a review

Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols
Add to cart successfully.