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PSD95

Product code: R1508-4


  • Overview

  • Product name PSD95
  • Molecular Wt 80kDa
  • Description PSD-95 is a member of the membrane-associated guanylate kinase(MAGUK) family. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the?clustering of receptors, ion channels, and associated signaling proteins.PSD-95 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density ofneurons,and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin,NMDA receptors,AMPA receptors, and potassium channels.It plays an important role in synaptic plasticity and the stabilization of synaptic changes during?long-term potentiation.
  • Species reactivity Human, mouse, rat
  • Tested applications WB,IHC,FC
  • Antibody type Rabbit Polyclonal Antibody
  • Immunogen peptide
  • Positive control A172, mouse brain, SHG-44, N2A, rat brain
  • Conjugate Non-conjugated
  • Alternative names Discs large homolog 4 antibody
    Disks large homolog 4 antibody
    DLG 4 antibody
    Dlg4 antibody
    DLG4_HUMAN antibody
    FLJ97752 antibody
    FLJ98574 antibody
    Human post synaptic density protein 95 antibody
    Post synaptic density protein 95 antibody
    Postsynaptic density protein 95 antibody
    PSD 95 antibody
    PSD-95 antibody
    PSD95 antibody
    SAP 90 antibody
    SAP-90 antibody
    SAP90 antibody
    Synapse associated protein 90 antibody
    Synapse-associated protein 90 antibody
    Tax interaction protein 15 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Peptide affinity purified
  • Subcellular location Cell membrane
  • Database links P78352
  • Applications

    WB: 1:1000
    IHC: 1:50

  • Publishing research using PSD95? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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