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Integrin beta 1 [SA40-08]

Product code: ET1601-17

  • Overview

  • Product name Integrin beta 1
  • Molecular Wt 140 kDa
  • Description Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). Integrins are obligate heterodimers containing two distinct chains, called the α (alpha) and β (beta) subunits. The molecular mass of the integrin subunits can vary from 90 kDa to 160 kDa. Beta subunits have four cysteine-rich repeated sequences. Both α and β subunits bind several divalent cations. Integrins have two main functions: Attachment of the cell to the ECM and signal transduction from the ECM to the cell. However, they are also involved in a wide range of other biological activities, including immune patrolling, cell migration, and binding to cells by certain viruses, such as adenovirus, echovirus, hantavirus, and foot and mouth disease viruses. Research studies have implicated β1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis.
  • Species reactivity Human, Mouse, Rat, zebrafish
  • Tested applications WB,IHC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control Hela, NIH/3T3, human liver cancer tissue, human colon cancer tissue, mouse stomach tissue.
  • Conjugate Non-conjugated
  • Clone number SA40-08
  • Alternative names beta1 integrin antibody
    CD29 antibody
    Fibronectin receptor subunit beta antibody
    FNRB antibody
    Glycoprotein IIa antibody
    GP IIa antibody
    GPIIA antibody
    Integrin beta-1 antibody
    integrin VLA-4 beta subunit antibody
    Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) antibody
    ITB1_HUMAN antibody
    ITGB1 antibody
    MDF2 antibody
    MSK12 antibody
    OTTHUMP00000019420 antibody
    Very late activation protein, beta polypeptide antibody
    VLA BETA antibody
    VLA-4 subunit beta antibody
    VLA-BETA antibody
    VLAB antibody
    VLAbeta antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Cell Membrane, Cell projection, Cleavage furrow
  • Database links P05556(Human)
  • Applications

    WB: 1:1,000-1:5,000
    IHC: 1:50-1:200

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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