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Product code: R1310-4

  • Overview

  • Product name PRDM14
  • Molecular Wt ~64kDa
  • Description PR domain zinc finger protein 14 is a transcription factor that has both positive and negative roles on transcription. It is expressed in embryonic stem cells and tends to be overexpressed in breast cancer. PRDM14 is required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. It may play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. PRDM14 directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer.
  • Species reactivity Human,mouse
  • Tested applications WB,ICC,IHC
  • Antibody type Rabbit Polyclonal Antibody
  • Immunogen peptide
  • Positive control Human embryonic stem cells, human lung, MCF-7
  • Conjugate Non-conjugated
  • Alternative names MGC59730 antibody
    PFM 11 antibody
    PFM11 antibody
    PR domain containing 14 antibody
    PR domain zinc finger protein 14 antibody
    PR domain-containing protein 14 antibody
    PRD14_HUMAN antibody
    PRDM 14 antibody
    PRDM14 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Immunogen affinity purified
  • Subcellular location Nucleus
  • Database links Q9GZV8
  • Applications

    WB: 1:500-1:1,000
    IHC: 1:100

  • Publishing research using PRDM14? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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