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Neuropilin 1 [A3-D1]

Product code: M0910-5


  • Overview

  • Product name Neuropilin 1
  • Molecular Wt 103 kDa
  • Description The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
  • Species reactivity Human, Mouse
  • Tested applications WB,ICC,IHC
  • Antibody type Mouse Monoclonal Antibody
  • Immunogen Recombinant protein
  • Positive control Hela, mouse brain tissue
  • Conjugate Non-conjugated
  • Clone number A3-D1
  • Alternative names AI851453 antibody
    BCTL1 antibody
    Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody
    Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody
    BTCL1 antibody
    C130005O10Rik antibody
    FLJ41325 antibody
    Neto1 antibody
    NETO1_HUMAN antibody
    Neuropilin and tolloid like 1 antibody
    Neuropilin and tolloid-like protein 1 antibody
    RGD1566269 antibody
  • Properties

  • Form Liquid
  • Concentration 2 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgM
  • Purity ProA affinity purified
  • Subcellular location Cell membrane
  • Database links O14786(Human)
    P97333(Mouse)
  • Applications

    WB: 1:1,000-1:10,000
    ICC: 1:100-1:500
    IHC: 1:50

  • Publishing research using Neuropilin 1? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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