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Product code: R1308-3

  • Overview

  • Product name MAPK14
  • Molecular Wt ~41kDa
  • Description Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response.
  • Species reactivity Human,mouse,rat
  • Tested applications WB,ICC,IHC,FC
  • Antibody type Rabbit Polyclonal Antibody
  • Immunogen peptide
  • Positive control Hela, Jurkat, HepG2, 293T, NIH/3T3, N2A, PC12
  • Conjugate Non-conjugated
  • Alternative names CSAID Binding Protein 1 antibody
    CSAID binding protein antibody
    CSAID-binding protein antibody
    Csaids binding protein antibody
    CSBP 1 antibody
    CSBP 2 antibody
    CSBP antibody
    CSBP1 antibody
    CSBP2 antibody
    CSPB1 antibody
    Cytokine suppressive anti-inflammatory drug-binding protein antibody
    EXIP antibody
    MAP kinase 14 antibody
    MAP kinase MXI2 antibody
    MAP kinase p38 alpha antibody
    MAPK 14 antibody
    MAPK14 antibody
    MAX interacting protein 2 antibody
    MAX-interacting protein 2 antibody
    Mitogen Activated Protein Kinase 14 antibody
    Mitogen activated protein kinase p38 alpha antibody
    Mitogen-activated protein kinase 14 antibody
    Mitogen-activated protein kinase p38 alpha antibody
    MK14_HUMAN antibody
    Mxi 2 antibody
    MXI2 antibody
    p38 ALPHA antibody
    p38 antibody
    p38 MAP kinase antibody
    p38 MAPK antibody
    p38 mitogen activated protein kinase antibody
    p38ALPHA antibody
    p38alpha Exip antibody
    PRKM14 antibody
    PRKM15 antibody
    RK antibody
    SAPK2A antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Immunogen affinity purified
  • Subcellular location Nucleus, Cytoplasm
  • Database links Q16539
  • Applications

    WB: 1:1,000
    ICC: 1:100-1:200

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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