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p53 [SA39-07]

Product code: ET1601-13


  • Overview

  • Product name p53
  • Molecular Wt 44/53 kDa (Human), 41kDa (Zebrafish)
  • Description The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. P53 is found in increased amounts in a wide variety of transformed cells. P53 is frequently mutated or inactivated in about 60% of cancers.
  • Species reactivity Human, Zebrafish
  • Tested applications WB,ICC/IF,IHC-P
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen Synthetic peptide within human p53 aa 1-100.
  • Positive control 293T cell lysate, 293 cell lysate, zebrafish tissue lysates, A549, SW480, human liver carcinoma tissue, human breast carcinoma tissue.
  • Conjugate Non-conjugated
  • Clone number SA39-07
  • Alternative names Antigen NY-CO-13 antibody
    BCC7 antibody
    Cellular tumor antigen p53 antibody
    FLJ92943 antibody
    LFS1 antibody
    Mutant tumor protein 53 antibody
    p53 antibody
    p53 tumor suppressor antibody
    P53_HUMAN antibody
    Phosphoprotein p53 antibody
    Tp53 antibody
    Transformation related protein 53 antibody
    TRP53 antibody
    Tumor protein 53 antibody
    Tumor protein p53 antibody
    Tumor suppressor p53 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Protein A affinity purified.
  • Subcellular location Cytoplasm, Nucleus, Endoplasmic reticulum, Mitochondrion matrix
  • Database links P04637(Human)
  • Applications

    WB: 1:500-1:5,000
    ICC/IF: 1:50-1:200
    IHC-P: 1:50-1:200

  • Publishing research using p53? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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