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CD34

Product code: 0108-2


  • Overview

  • Product name CD34
  • Molecular Wt 90 kDa
  • Description CD34 is a heavily glycosylated type I transmembrane molecule, that can be phoshorylated by a variety of kinases including Protein kinase C and Tyrosine kinases. CD34 antigen is expressed on small vessel endothelial cells and tumors of epithelial origin. CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. So CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC
  • Species reactivity Human, zebrafish
  • Tested applications WB,ICC,IHC,FC
  • Antibody type Rabbit Polyclonal Antibody
  • Immunogen peptide
  • Positive control Human brain, mouse brain, mouse testis, Mouse thymus, mouse spleen, Jurkat, TF-1, F9, human embryonic stem cell, human tonsil tissue
  • Conjugate Non-conjugated
  • Alternative names CD34 antibody
    CD34 antigen antibody
    CD34 molecule antibody
    CD34_HUMAN antibody
    Cluster designation 34 antibody
    Hematopoietic progenitor cell antigen CD34 antibody
    HPCA1 antibody
    Mucosialin antibody
    OTTHUMP00000034733 antibody
    OTTHUMP00000034734 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Immunogen affinity purified
  • Subcellular location Cell membrane
  • Database links P28906
  • Applications

    WB: 1:500-1:1,000
    ICC: 1:100
    IHC: 1:3,000
    FC: 1:50-1:100

  • Publishing research using CD34? Please let us know so that we can cite the reference in this datasheet.

  • Gu, B., Zhang, J., Wu, Y., Zhang, X., Tan, Z., Lin, Y., . . . Zhang, M. (2011). Proteomic analyses reveal common promiscuous patterns of cell surface proteins on human embryonic stem cells and sperms. PLoS One, 6(5), e19386. PMID: 21559292
  • Gu, B., Zhang, J., Wu, Y., Zhang, X., Tan, Z., Lin, Y., . . . Zhang, M. (2011). Proteomic analyses reveal common promiscuous patterns of cell surface proteins on human embryonic stem cells and sperms. PLoS One, 6(5), e19386. PMID: 21559292

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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