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CCDC111 [10-B3]

Product code: M1311-4

  • Overview

  • Product name CCDC111
  • Molecular Wt 64kDa
  • Description DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. PRIMPOL shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. It is involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. PRIMPOL is required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. PRIMPOL has non-overlapping function with POLH.
  • Species reactivity Human
  • Tested applications ICC,IHC
  • Antibody type Mouse Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control HepG2, human colon
  • Conjugate Non-conjugated
  • Clone number 10-B3
  • Alternative names CC111_HUMAN antibody
    CCDC111 antibody
    Coiled coil domain containing 111 antibody
    Coiled-coil domain-containing protein 111 antibody
    DNA-directed primase/polymerase protein antibody
    MYP22 antibody
    Primase and polymerase (DNA directed) antibody
    PRIMPOL antibody
  • Properties

  • Form Liquid
  • Concentration 2 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG1
  • Purity ProG affinity purified
  • Subcellular location Nucleus
  • Database links Q96LW4
  • Applications

    ICC: 1:100-1:200
    IHC: 1:200

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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