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Glucose Transporter GLUT1 [SA0377]

Product code: ET1601-10

  • Overview

  • Product name Glucose Transporter GLUT1
  • Molecular Wt 54 kDa
  • Description Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter, Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane, and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve-pass transmembrane proteins (12TM) whose carboxy-termini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.
  • Species reactivity Human, Mouse, (Predicted: Rat)
  • Tested applications WB,ICC/IF,IHC-P,FC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen Synthetic peptide within C-terminal human GLUT1.
  • Positive control Hela cell lysate, Sk-Br-3 cell lysate, NIH/3T3 cell lysate, HepG2 cell lysate, Hela, MCF-7, HepG2, human liver tissue, human placenta tissue, human liver carcinoma tissue, human kidney tissue, mouse liver tissue, mouse kidney tissue.
  • Conjugate Non-conjugated
  • Clone number SA0377
  • Alternative names Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity) antibody
    CSE antibody
    DYT17 antibody
    DYT18 antibody
    DYT9 antibody
    EIG12 antibody
    erythrocyte/brain antibody
    Erythrocyte/hepatoma glucose transporter antibody
    facilitated glucose transporter member 1 antibody
    Glucose transporter 1 antibody
    Glucose transporter type 1 antibody
    Glucose transporter type 1, erythrocyte/brain antibody
    GLUT antibody
    GLUT-1 antibody
    GLUT1 antibody
    GLUT1DS antibody
    GLUTB antibody
    GT1 antibody
    GTG1 antibody
    Gtg3 antibody
    GTR1_HUMAN antibody
    HepG2 glucose transporter antibody
    HTLVR antibody
    Human T cell leukemia virus (I and II) receptor antibody
    MGC141895 antibody
    MGC141896 antibody
    PED antibody
    RATGTG1 antibody
    Receptor for HTLV 1 and HTLV 2 antibody
    SLC2A1 antibody
    Solute carrier family 2 (facilitated glucose transporter), member 1 antibody
    Solute carrier family 2 antibody
    Solute carrier family 2, facilitated glucose transporter member 1 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Protein A affinity purified.
  • Subcellular location Cell membrane, Melanosome
  • Database links SwissProt: P11166 Human
    SwissProt: P17809 Mouse
    SwissProt: P11167 Rat
  • Applications

    WB: 1:500-1:1,000
    ICC/IF: 1:50-1:200
    IHC-P: 1:50-1:200
    FC: 1:50-1:100

  • Publishing research using Glucose Transporter GLUT1? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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