Rabbit polyclonal primary
ZBTB48 Antibody (ER1706-82)
Mouse spleen tissue lysate, HepG2, PC-3M, SH-SY5Y, human liver cancer tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified
0610011D15Rik antibody; AI327031 antibody; GLI Kruppel family member HKR3 antibody; HKR3 antibody; Krueppel related zinc finger protein 3 antibody; Krueppel-related zinc finger protein 3 antibody; OTTMUSP00000031803 antibody; pp9964 antibody; Protein HKR3 antibody; RP23-445E20.3 antibody; ZBT48_HUMAN antibody; ZBTB 48 antibody; Zbtb48 antibody; Zinc finger and BTB domain containing 48 antibody; Zinc finger and BTB domain containing protein 48 antibody; Zinc finger and BTB domain-containing protein 48 antibody; Zinc finger protein 855 antibody; ZNF855 antibody
Belongs to the krueppel C2H2-type zinc-finger protein family.
Detected in adrenal gland and neuroblastoma.
Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.