Mouse monoclonal primary
YKL-40/CHI3L1 Monoclonal Antibody (EM1902-31)
Recombinant protein within extracellular domain of human chi3l1.
THP-1 cell lysates, human tonsil tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein G affinity purified.
39 kDa synovial protein antibody; ASRT7 antibody; Cartilage glycoprotein 39 antibody; CGP-39 antibody; CGP39 antibody; CH3L1_HUMAN antibody; CHI3L1 antibody; chitinase 3 like 1 (cartilage glycoprotein 39) antibody; chitinase 3 like 1 antibody; Chitinase 3 like protein 1 precursor antibody; chitinase antibody; Chitinase-3-like protein 1 antibody; Chondrocyte protein YKL40 antibody; GP 39 antibody; GP-39 antibody; GP39 antibody; HC gp39 antibody; HCGP 3P antibody; hCGP-39 antibody; HCgp39 antibody; YKL 40 antibody; YKL-40 antibody; YKL40 antibody; YYL 40 antibody
Belongs to the glycosyl hydrolase 18 family.
Present in activated macrophages, articular chondrocytes, synovial cells as well as in liver. Very low or undetectable expression in non-inflammatory colon. Undetectable in muscle tissues, lung, pancreas, mononuclear cells, or fibroblasts.
Extracellular space, Endoplasmic reticulum, Cytoplasm.
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.