Recombinant Rabbit monoclonal primary
WSTF Recombinant Rabbit Monoclonal Antibody [JG36-32] (ET7108-32)
Recombinant protein within c-terminal human wstf.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
baz1b antibody; BAZ1B_HUMAN antibody; Bromodomain adjacent to zinc finger domain protein 1B antibody; hWALP 2 antibody; hWALP-2 antibody; hWALP2 antibody; transcription factor WSTF antibody; Tyrosine-protein kinase BAZ1B antibody; WALP-2 antibody; WALP2 antibody; WBRS 9 antibody; WBRS-9 antibody; WBRS9 antibody; WBSC 10 antibody; WBSC-10 antibody; WBSC10 antibody; WBSCR10 antibody; WBSCR9 antibody; Williams Beuren syndrome chromosome region 9 protein antibody; Williams syndrome transcription factor antibody; Williams-Beuren syndrome chromosomal region 10 protein antibody; Williams-Beuren syndrome chromosomal region 9 protein antibody; WSTF antibody
Belongs to the WAL family. BAZ1B subfamily.
Ubiquitously expressed with high levels of expression in heart, brain, placenta, skeletal muscle and ovary.
Expressed at equal levels in 19-23 weeks old fetal tissues.
Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.