Lane 1: PC-3M
Lane 2: Mouse brain tissue
Lane 3: Jurkat
Lane 4: Human lung tissue
Rabbit polyclonal primary
WNT2 Antibody (ER1511-4)
PC-3M, mouse brain tissue, Jurkat, human lung tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified
IRP, WNT2, INT1L1, IRP
Belongs to the Wnt family.
Expressed in brain in the thalamus, in fetal and adult lung and in placenta.
Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Secreted, extracellular space, extracellular matrix.
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).