Rabbit polyclonal primary
WASL Antibody (ER1803-16)
Recombinant protein within human wasl aa 100-300.
SH-SY-5Y, SiHa, SK-Br-3, rat brain tissue, human small intestine tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
55 kDa (Predicted band size)
WASP family, verprolin homology domain-containing protein 1 antibody; WASP family member 1 antibody; FLJ31482 antibody; homology of dictyostelium scar 1 antibody; KIAA0269 antibody; Protein WAVE-1 antibody; Protein WAVE1 antibody; scar, Dictyostelium, homology of, 1 antibody; SCAR1 antibody; Similar to a plant extensin like protein antibody; Verprolin homology domain containing protein 1 antibody; Verprolin homology domain-containing protein 1 antibody; WAS protein family, member 1 antibody; Wasf1 antibody; WASF1_HUMAN antibody; WASL antibody; WASP family 1 antibody; WASP family protein member 1 antibody; WASP family, verprolin homology domain-containing protein antibody; WAVE antibody; WAVE1 antibody; Wiskott Aldrich syndrome protein family member 1 antibody; Wiskott-Aldrich syndrome protein family member 1 antibody
Phosphorylation at Ser-242, Tyr-256, Ser-484 and Ser-485 enhances actin polymerization activity.
Cytoplasm. Cytoskeleton. Nucleus.
Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. Plays a role in dendrite spine morphogenesis.