PRODUCT CODE: ER1802-40

Vitamin D Receptor Antibody (ER1802-40)

Applications

  • WB

  • FC

REACTIVITY

  • Human

Western blot analysis of Vitamin D Receptor on PC-3M cell and human small intestine tissue lysate using anti-Vitamin D Receptor antibody at 1/500 dilution.
  • Western blot analysis of Vitamin D Receptor on PC-3M cell and human small intestine tissue lysate using anti-Vitamin D Receptor antibody at 1/500 dilution.
  • Flow cytometric analysis of LOVO cells with Vitamin D Receptor antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Western blot analysis of Vitamin D Receptor on PC-3M cell and human small intestine tissue lysate using anti-Vitamin D Receptor antibody at 1/500 dilution.

Applications

  • WB

  • FC

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

Vitamin D Receptor Antibody (ER1802-40)

Immunogen

Peptide

Host

Rabbit

Positive Control

PC-3M, Human small intestine tissue lysate, LOVO.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified

MOLECULAR WEIGHT

48 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • FC

  • 1:50-1:100

TARGET

UNIPROT #

PROTEIN NAME

Vitamin D3 receptor

GENE NAME

VDR

SYNONYMS

VDR, NR1I1

SEQUENCE SIMILARITIES

Belongs to the nuclear hormone receptor family. NR1 subfamily.

SUBCELLULAR LOCATION

Nucleus. Cytoplasm. Note=Localizes mainly to the nucleus. Localization to the nucleus is enhanced by vitamin D3.

FUNCTION

Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Plays a central role in calcium homeostasis (By similarity).