Lane 1: 293T
Lane 2: Daudi
Lane 3: Mouse testis
Lane 4: Rat brain
Rabbit polyclonal primary
USP13 Antibody (ER1803-09)
Recombinant protein within human usp13 aa 550-800.
293T, Daudi, mouse testis tissue, rat brain tissue, A431, MG-63.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Deubiquitinating enzyme 13 antibody; Isopeptidase T 3 antibody; Isopeptidase T-3 antibody; Isopeptidase T3 antibody; ISOT 3 antibody; ISOT-3 antibody; ISOT3 antibody; Ubiquitin carboxyl terminal hydrolase 13 antibody; Ubiquitin carboxyl-terminal hydrolase 13 antibody; Ubiquitin specific peptidase 13 (isopeptidase T3) antibody; Ubiquitin specific peptidase 13 antibody; Ubiquitin specific processing protease 13 antibody; Ubiquitin specific protease 13 antibody; Ubiquitin thioesterase 13 antibody; Ubiquitin thiolesterase 13 antibody; Ubiquitin-specific-processing protease 13 antibody; UBP13 antibody; UBP13_HUMAN antibody; USP 13 antibody; USP13 antibody
Belongs to the peptidase C19 family.
Highly expressed in ovary and testes.
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP13 (ubiquitin specific peptidase 13), also known as ISOT3 (Isopeptidase T-3), is an 863 amino acid protein that belongs to the peptidase C19 family and contains one UBP-type zinc finger and two UBA domains. Highly expressed in testicular and ovarian tissue, USP13 functions to catalyze the water-dependent conversion of a ubiquitin C-terminal thioester to a thiol and a free ubiquitin.