Rabbit polyclonal primary
TMEM119 Antibody (ER2001-37)
Synthetic peptide within human transmembrane protein 119 aa 120-170.
SHSY5Y cell lysates.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Predicted band size: 29 kDa.
Transmembrane protein 119 Osteoblast induction factor TMEM119 OBIF
Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane.
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts . May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).