Rabbit polyclonal primary
TMEM119 Antibody (ER2001-37)
Synthetic peptide within human transmembrane protein 119 aa 120-170.
SHSY5Y cell lysates.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Predicted band size: 29 kDa.
OBIF antibody; Osteoblast induction factor antibody; PSEC0199 antibody; Transmembrane protein 119 antibody; UNQ731/PRO1415 antibody
Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane.
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts . May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).