Rabbit polyclonal primary
SSB Antibody (ER2001-50)
Recombinant protein within human ssb aa 150-350.
Daudi cell lysates, human lung tissue lysates, JAR, human pancreas tissue, human stomach cancer tissue, human kidney tissue, human thyroid tissue, HCT116.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Lupus La protein La autoantigen La ribonucleoprotein Sjoegren syndrome type B antigen SS-B
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.