Recombinant Rabbit monoclonal primary
Recombinant WASF2 Monoclonal Antibody (ET1610-69)
Human placenta tissue, human kidney tissue, mouse kidney tissue, mouse placenta tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Wiskott-Aldrich syndrome protein family member 2
WASP family protein member 2, WASF2
Belongs to the SCAR/WAVE family.
Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.
Cytoplasm, cytoskeleton. Note=At the interface between the lamellipodial actin meshwork and the membrane.
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.