PRODUCT CODE: ET1610-69

Recombinant WASF2 Monoclonal Antibody (ET1610-69)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of WASF2 on human placenta lysates using anti-WASF2 antibody at 1/1,000 dilution.
  • Western blot analysis of WASF2 on human placenta lysates using anti-WASF2 antibody at 1/1,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-WASF2 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-WASF2 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-WASF2 antibody. Counter stained with hematoxylin.
Western blot analysis of WASF2 on human placenta lysates using anti-WASF2 antibody at 1/1,000 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant WASF2 Monoclonal Antibody (ET1610-69)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human placenta tissue, human kidney tissue, mouse kidney tissue, mouse placenta tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

SC66-05

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

54 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000-1:5,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

Wiskott-Aldrich syndrome protein family member 2

GENE NAME

WASF2

SYNONYMS

WASP family protein member 2, WASF2

SEQUENCE SIMILARITIES

Belongs to the SCAR/WAVE family.

TISSUE SPECIFICITY

Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.

SUBCELLULAR LOCATION

Cytoplasm, cytoskeleton. Note=At the interface between the lamellipodial actin meshwork and the membrane.

FUNCTION

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.