PRODUCT CODE: ET7107-09

Recombinant Versican Monoclonal Antibody (ET7107-09)

  • Recombinant

Applications

  • IHC-P

  • WB

REACTIVITY

  • Human

  • Mouse

Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Versican antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Versican antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Versican antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Versican antibody. Counter stained with hematoxylin.

Applications

  • IHC-P

  • WB

REACTIVITY

  • Human

  • Mouse

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant Versican Monoclonal Antibody (ET7107-09)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human spleen tissue, mouse brain tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JB42-32

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

373/265/182/74 kDa

Isotype

IgG

APPLICATION DILUTION

  • IHC-P

  • 1:50-1:200

  • WB

  • 1:500

TARGET

UNIPROT #

PROTEIN NAME

Versican core protein

GENE NAME

VCAN

SYNONYMS

Chondroitin sulfate proteoglycan 2, GHAP, VCAN, CSPG2

SEQUENCE SIMILARITIES

Belongs to the aggrecan/versican proteoglycan family.

TISSUE SPECIFICITY

Expressed in the retina (at protein level). Cerebral white matter and plasma. Isoform V0: Expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V1: Expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2: Restricted to normal brain and gliomas. Isoform V3: Found in all these tissues except medulloblastomas.

DEVELOPMENTAL STAGE

Expressed in developing photoreceptors and the interphotoreceptor matrix between 12 and 17 weeks post conception (at protein level). Disappears in aorta after the cartilage development.

POST-TRANSLATIONAL MODIFICATION

Phosphorylated by FAM20C in the extracellular medium.

SUBCELLULAR LOCATION

Secreted, extracellular space, extracellular matrix. Cell projection, cilium, photoreceptor outer segment. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.

FUNCTION

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.