Recombinant Rabbit monoclonal primary
Recombinant Syndecan 1 Monoclonal Antibody (ET1703-42)
A431, HepG2, NIH-3T3, Hela, human tonsil tissue, human kidney tissue, human lung tissue, mouse prostate tissue, mouse colon tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Belongs to the syndecan proteoglycan family.
Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Membrane. Secreted, extracellular exosome. Note=Shedding of the ectodomain produces a soluble form.
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP.