PRODUCT CODE: ET1609-11

Recombinant SOX18 Monoclonal Antibody (ET1609-11)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of SOX18 on K562 cells lysates using anti-SOX18 antibody at 1/1,000 dilution.
  • Western blot analysis of SOX18 on K562 cells lysates using anti-SOX18 antibody at 1/1,000 dilution.
Western blot analysis of SOX18 on K562 cells lysates using anti-SOX18 antibody at 1/1,000 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant SOX18 Monoclonal Antibody (ET1609-11)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

K562.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

ST43-02

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

41 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IHC-P:1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

Transcription factor SOX-18

GENE NAME

SOX18

SYNONYMS

SOX18

TISSUE SPECIFICITY

Detected in heart, lung, placenta, skeletal muscle, liver, kidney, spleen, prostate, ovary, msosmall intestine and colon.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers. Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17. Interaction with MEF2C enhances transcriptional activation. Besides, required for normal hair development.