Recombinant Rabbit monoclonal primary
Recombinant SOX1 Monoclonal Antibody (ET1701-38)
SHG-44, rat brain tissue, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Sex determining region Y box 1 antibody; sox1 antibody; SOX1_HUMAN antibody; SRY antibody; SRY box containing gene 1 antibody; SRY related HMG box gene 1 antibody; Transcription factor Sox-1 antibody
Mainly expressed in the developing central nervous system.
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.