Recombinant Rabbit monoclonal primary
Recombinant RRM2 Monoclonal Antibody (ET1705-62)
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
cb111 antibody; chunp6884 antibody; etID309896.20 antibody; R2 antibody; reductase M2 polypeptide variant 1 antibody; reductase M2 polypeptide variant 2 antibody; reductase M2 polypeptide variant 3a antibody; reductase M2 polypeptide variant 3b antibody; reductase M2 polypeptide variant 3c antibody; reductase M2 polypeptide variant 3d antibody; Ribonucleoside-diphosphate reductase subunit M2 antibody; Ribonucleotide reductase M2 antibody; Ribonucleotide reductase M2 polypeptide antibody; Ribonucleotide reductase M2 subunit antibody; ribonucleotide reductase protein r2 class I antibody; Ribonucleotide reductase regulatory subunit M2 antibody; Ribonucleotide reductase small chain antibody; Ribonucleotide reductase small subunit antibody; Ribonucleotide reductase, R2 subunit antibody; RIR2_HUMAN antibody; RR2 antibody; RR2M antibody; RRM2 antibody
Belongs to the ribonucleoside diphosphate reductase small chain family.
Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
Belongs to the ribonucleoside diphosphate reductase small chain family. Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.it have two regulatory sites: the specificity site, which controls substrate specificity, and the activity site which regulates overall catalytic activity. A substrate-binding catalytic site, located on M1, is formed only in the presence of the second subunit M2.