Lane 1: HCT116
Lane 2: Jurkat
Lane 3: 293T
Recombinant Rabbit monoclonal primary
Recombinant RALBP1 Monoclonal Antibody (ET1610-88)
HCT116, Jurkat, human breast carcinoma tissue, human pancreas tissue, mouse lung tissue, mouse pancreas tissue, mouse testis tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
RalA-binding protein 1
DNP-SG ATPase, RALBP1
Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes.
Membrane; Peripheral membrane protein.
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.