PRODUCT CODE: ET7106-58

Recombinant PTBP1 Monoclonal Antibody (ET7106-58)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of PTBP1 on different lysates using anti-PTBP1 antibody at 1/500 dilution.<br />
  Positive control:<br />
  Lane 1: K562 <br />
  Lane 2: Jurkat<br />
  Lane 3: Mouse colon tissue
  • Western blot analysis of PTBP1 on different lysates using anti-PTBP1 antibody at 1/500 dilution.<br />
  Positive control:<br />
  Lane 1: K562 <br />
  Lane 2: Jurkat<br />
  Lane 3: Mouse colon tissue
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
Western blot analysis of PTBP1 on different lysates using anti-PTBP1 antibody at 1/500 dilution.
Positive control:
Lane 1: K562
Lane 2: Jurkat
Lane 3: Mouse colon tissue

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant PTBP1 Monoclonal Antibody (ET7106-58)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Jurkat, A549, LOVO, human tonsil tissue, human skin tissue, human kidney tissue, mouse colon tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JU41-20

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

57 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-2,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

PTBP1

SYNONYMS

57 kDa RNA binding protein PPTB 1 antibody; 57 kDa RNA-binding protein PPTB-1 antibody; Heterogeneous nuclear ribonucleoprotein I antibody; Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody; hnRNP I antibody; HNRNP-I antibody; HNRNPI antibody; HNRPI antibody; MGC10830 antibody; MGC8461 antibody; Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody; Polypyrimidine Tract Binding Protein 1 antibody; Polypyrimidine tract binding protein antibody; Polypyrimidine tract-binding protein 1 antibody; pPTB antibody; PTB 1 antibody; PTB 2 antibody; PTB 3 antibody; PTB 4 antibody; PTB antibody; PTB T antibody; PTB1 antibody; PTB2 antibody; PTB3 antibody; PTB4 antibody; PTBP 1 antibody; PTBP1 antibody; PTBP1_HUMAN antibody; PTBT antibody; RNA Binding Protein antibody

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.