Lane 1: Hela
Lane 2: Mouse Thymus
Lane 3: SH-SY5Y
Recombinant Rabbit monoclonal primary
Recombinant PSD93 Monoclonal Antibody (ET1705-90)
Hela cell lysate, SH-SY5Y cell lysate, SH-SY5Y.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Channel associated protein of synapse 110 antibody; Channel associated protein of synapses 110kD antibody; Channel-associated protein of synapse-110 antibody; Chapsyn 110 antibody; Chapsyn-110 antibody; Chapsyn110 antibody; Discs, large homolog 2 (Drosophila) antibody; Disks large homolog 2 antibody; DKFZp781D1854 antibody; DKFZp781E0954 antibody; Dlg 2 antibody; dlg2 antibody; DLG2_HUMAN antibody; Dlgh 2 antibody; Dlgh2 antibody; FLJ37266 antibody; Gm1197 antibody; MGC131811 antibody; Postsynaptic density protein PSD 93 antibody; Postsynaptic density protein PSD-93 antibody; Postsynaptic density protein PSD93 antibody; PSD 93 antibody; PSD93 antibody
Belongs to the MAGUK family.
Palmitoylation of isoform 1 is not required for targeting to postsynaptic density.
Cell membrane, postsynaptic density, synapse, Membrane, axon, perikaryon.
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.