PRODUCT CODE: ET1705-90

Recombinant PSD93 Monoclonal Antibody (ET1705-90)

  • Recombinant

Applications

  • WB

  • FC

  • IP

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of PSD93 on different lysates using anti-PSD93 antibody at 1/1,000 dilution.<br />
 Positive control:<br />
 Lane 1: Hela<br />
 Lane 2: Mouse Thymus<br />
 Lane 3: SH-SY5Y
  • Western blot analysis of PSD93 on different lysates using anti-PSD93 antibody at 1/1,000 dilution.<br />
 Positive control:<br />
 Lane 1: Hela<br />
 Lane 2: Mouse Thymus<br />
 Lane 3: SH-SY5Y
  • Flow cytometric analysis of SH-SY5Y cells with PSD93 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Western blot analysis of PSD93 on different lysates using anti-PSD93 antibody at 1/1,000 dilution.
Positive control:
Lane 1: Hela
Lane 2: Mouse Thymus
Lane 3: SH-SY5Y

Applications

  • WB

  • FC

  • IP

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant PSD93 Monoclonal Antibody (ET1705-90)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Hela cell lysate, SH-SY5Y cell lysate, SH-SY5Y.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JM41-04

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A affinity purified.

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • FC

  • 1:50-1:100

  • IP

  • 1:10-1:50

TARGET

UNIPROT #

PROTEIN NAME

PSD93

SYNONYMS

Channel associated protein of synapse 110 antibody; Channel associated protein of synapses 110kD antibody; Channel-associated protein of synapse-110 antibody; Chapsyn 110 antibody; Chapsyn-110 antibody; Chapsyn110 antibody; Discs, large homolog 2 (Drosophila) antibody; Disks large homolog 2 antibody; DKFZp781D1854 antibody; DKFZp781E0954 antibody; Dlg 2 antibody; dlg2 antibody; DLG2_HUMAN antibody; Dlgh 2 antibody; Dlgh2 antibody; FLJ37266 antibody; Gm1197 antibody; MGC131811 antibody; Postsynaptic density protein PSD 93 antibody; Postsynaptic density protein PSD-93 antibody; Postsynaptic density protein PSD93 antibody; PSD 93 antibody; PSD93 antibody

SEQUENCE SIMILARITIES

Belongs to the MAGUK family.

POST-TRANSLATIONAL MODIFICATION

Palmitoylation of isoform 1 is not required for targeting to postsynaptic density.

SUBCELLULAR LOCATION

Cell membrane, postsynaptic density, synapse, Membrane, axon, perikaryon.

FUNCTION

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.