PRODUCT CODE: ET1702-42

Recombinant Prealbumin Monoclonal Antibody (ET1702-42)

  • Recombinant

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

Western blot analysis of Prealbumin on human lung lysates using anti-Prealbumin antibody at 1/1,000 dilution.
  • Western blot analysis of Prealbumin on human lung lysates using anti-Prealbumin antibody at 1/1,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Prealbumin antibody. Counter stained with hematoxylin.
Western blot analysis of Prealbumin on human lung lysates using anti-Prealbumin antibody at 1/1,000 dilution.

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant Prealbumin Monoclonal Antibody (ET1702-42)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human liver tissue, human lung tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JF1016

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

16 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000-1:2,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

Transthyretin

GENE NAME

TTR

SYNONYMS

TTR

SEQUENCE SIMILARITIES

Belongs to the transthyretin family.

TISSUE SPECIFICITY

Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver.

POST-TRANSLATIONAL MODIFICATION

Not glycosylated under normal conditions. Following unfolding, caused for example by variant AMYL-TTR 'Gly-38', the cryptic Asn-118 site is exposed and glycosylated by STT3B-containing OST complex, leading to its degradation by the ER-associated degradation (ERAD) pathway.

SUBCELLULAR LOCATION

Secreted. Cytoplasm.

FUNCTION

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.