Applications
-
WB
-
ICC
-
FC
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Recombinant Rabbit monoclonal primary
Product Name
Recombinant Plexin A1 Monoclonal Antibody (ET1706-17)
Immunogen
Recombinant protein
Host
Rabbit
Positive Control
LOVO.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JU50-37
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein A purified.
MOLECULAR WEIGHT
211 kDa
Isotype
IgG
APPLICATION DILUTION
-
ICC
-
1:50-1:200
-
FC
-
1:50-1:100
-
WB
-
1:500
TARGET
UNIPROT #
PROTEIN NAME
Plexin A1
SYNONYMS
NOV antibody; NOV/plexin A1 protein antibody; NOVP antibody; Plexin-A1 antibody; Plexin1 antibody; PlexinA1 antibody; PLXA1_HUMAN antibody; PLXN1 antibody; Plxna1 antibody; PLXNA1 protein antibody; Semaphorin receptor NOV antibody
SEQUENCE SIMILARITIES
Belongs to the plexin family.
TISSUE SPECIFICITY
Detected in fetal brain, lung, liver and kidney.
SUBCELLULAR LOCATION
Cell Membrane.
FUNCTION
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.