Lane 1: MCF-7 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: human tonsil tissue lysate
Recombinant Rabbit monoclonal primary
Recombinant PI 3 Kinase p55 gamma Monoclonal Antibody (ET1602-27)
Synthetic peptide within human pi 3 kinase p55 gamma aa 420-460.
MCF-7 cell lysate, Jurkat cell lysate, human tonsil tissue lysate, PC-3M, SH-SY5Y, mouse testis tissue, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
PI 3 Kinase p55 gamma
DKFZp686P05226 antibody; FLJ41892 antibody; OTTHUMP00000009783 antibody; OTTHUMP00000009786 antibody; p55 antibody; p55 gamma antibody; P55G_HUMAN antibody; p55PIK antibody; Phosphatidylinositol 3 kinase regulatory subunit gamma antibody; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 3 antibody; Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma) antibody; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma antibody; Phosphatidylinositol 3-kinase regulatory subunit gamma antibody; Phosphoinositide 3 kinase regulatory subunit 3 (gamma) antibody; Phosphoinositide 3 kinase regulatory subunit 3 antibody; Phosphoinositide 3 kinase regulatory subunit polypeptide 3 antibody; Phosphoinositide 3 kinase, regulatory subunit 3 (p55, gamma) antibody; Phosphoinositide 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma) antibody; PI3 kinase p85 subunit gamma antibody; PI3-kinase regulatory subunit gamma antibody; PI3-kinase subunit p55-gamma antibody; PI3K regulatory subunit gamma antibody; Pik3r3 antibody; PtdIns 3 kinase p85 gamma antibody; PtdIns-3-kinase regulatory subunit gamma antibody; PtdIns-3-kinase regulatory subunit p55-gamma antibody
Belongs to the PI3K p85 subunit family.
Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.
Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3’ position. PI 3-kinase p55γ (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55γ protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55γ mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55γ have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55γ interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.
Xiang, Bingyu et al.
Transplantation of Menstrual Blood-Derived Mesenchymal Stem Cells Promotes the Repair of LPS-Induced Acute Lung Injury. | International Journal of Molecular Sciences