Lane 1: HUVEC cell lysate
Lane 2: Hela cell lysate
Lane 2: PC-3M cell lysate
Recombinant Rabbit monoclonal primary
Recombinant Phospho eIF-2a(S51) Monoclonal Antibody (ET1603-14)
Synthetic phospho-peptide corresponding to residues surrounding ser51 of human eif-2a.
HUVEC cell lysate, Hela cell lysate, PC-3M cell lysate, Hela, human liver tissue, human pancreas tissue, mouse brain tissue, mouse placenta tissue, mouse pancreas tissue, human prostate carcinoma tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Eukaryotic translation initiation factor 2A
EIF2A, CDA02, MSTP004, MSTP089
Belongs to the WD repeat EIF2A family.
Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta.
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
Liu, Yin et al.
Retinoic acid receptor-related orphan receptor � stimulates adipose tissue inflammation by modulating endoplasmic reticulum stress. | The Journal of Biological Chemistry 
Tan, Zhouke et al.
Pharmacological and genetic inhibition of fatty acid-binding protein 4 alleviated cisplatin-induced acute kidney injury. | Journal of Cellular and Molecular Medicine 
Hao, Yan et al.
2-Methylquinazoline derivative 23BB as a highly selective histone deacetylase 6 inhibitor alleviated cisplatin-induced acute kidney injury. | Bioscience Reports 
Huang, Zhuo et al.
Activation of GPR120 by TUG891 ameliorated cisplatin-induced acute kidney injury via repressing ER stress and apoptosis. | Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie