Recombinant Rabbit monoclonal primary
Recombinant PAX7 Monoclonal Antibody (ET1612-60)
Hela cell lysates, MCF-7.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
FLJ37460 antibody; HUP1 antibody; OTTHUMP00000002534 antibody; Paired box 7 antibody; Paired box gene 7 antibody; Paired box homeotic gene 7 antibody; Paired box protein Pax-7 antibody; Paired domain gene 7 antibody; Paired domain gene HuP1 antibody; Pax7 antibody; PAX7 transcriptional factor antibody; PAX7/FKHR fusion gene, included antibody; PAX7_HUMAN antibody; PAX7B antibody; RGD1564360 antibody; RMS2 antibody
Belongs to the paired homeobox family.
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).