PRODUCT CODE: ET1704-79

Recombinant OGG1 Monoclonal Antibody (ET1704-79)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

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Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-OGG1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-OGG1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-OGG1 antibody. Counter stained with hematoxylin.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant OGG1 Monoclonal Antibody (ET1704-79)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human kidney tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JA18-13

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

39 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

OGG1

SYNONYMS

8 hydroxyguanine DNA glycosylase antibody; 8 oxoguanine DNA glycosylase 1 antibody; 8 oxoguanine DNA glycosylase antibody; AP lyase antibody; DNA (apurinic or apyrimidinic site) lyase antibody; DNA apurinic or apyrimidinic site lyase antibody; DNA lyase antibody; DNA-(apurinic or apyrimidinic site) lyase antibody; HMMH antibody; HOGG 1 antibody; HOGG1 antibody; MMH antibody; MUTM antibody; N glycosylase antibody; Ogg 1 antibody; Ogg1 antibody; OGG1_HUMAN antibody; OGH 1 antibody; OGH1 antibody

SEQUENCE SIMILARITIES

Belongs to the type-1 OGG1 family.

TISSUE SPECIFICITY

Ubiquitous.

SUBCELLULAR LOCATION

Mitochondrion. Nucleus

FUNCTION

DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.