Recombinant Rabbit monoclonal primary
Recombinant mGluR2 Monoclonal Antibody (ET1701-74)
SH-SY-5Y, SW480, Hela, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Metabotropic glutamate receptor 2
Belongs to the G-protein coupled receptor 3 family.
Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.
Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite.
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.