PRODUCT CODE: ET1703-84

Recombinant mGluR1 Monoclonal Antibody (ET1703-84)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of mGluR1 on rat brain cells lysates using anti-mGluR1 antibody at 1/500 dilution.
  • Western blot analysis of mGluR1 on rat brain cells lysates using anti-mGluR1 antibody at 1/500 dilution.
  • Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-mGluR1 antibody. Counter stained with hematoxylin. <br />
  • Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-mGluR1 antibody. Counter stained with hematoxylin. <br />
Western blot analysis of mGluR1 on rat brain cells lysates using anti-mGluR1 antibody at 1/500 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant mGluR1 Monoclonal Antibody (ET1703-84)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Mouse brain tissue, mouse kidney tissue, rat brain tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JM11-61

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

200 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

Metabotropic glutamate receptor 1

GENE NAME

GRM1

SYNONYMS

mGluR1, GRM1

SEQUENCE SIMILARITIES

Belongs to the G-protein coupled receptor 3 family.

TISSUE SPECIFICITY

Detected in brain.

SUBCELLULAR LOCATION

Cell membrane; Multi-pass membrane protein.

FUNCTION

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. May function in the light response in the retina (By similarity).