Lane 1: Hela cell lysate
Lane 2: Jurkat cell lysate
Recombinant Rabbit monoclonal primary
Recombinant Lamin B1 Monoclonal Antibody (ET1606-27)
Human liver tissue, human colon cancer tissue, human breast carcinoma tissue, mouse brain tissue, mouse colon tissue, mouse liver tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Belongs to the intermediate filament family.
B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Lin, Xiaoping et al.
Next-generation sequencing identified novel Desmoplakin frame-shift variant in patients with Arrhythmogenic cardiomyopathy. | Bmc Cardiovascular Disorders