Line 1: Hela
Line 2: human brain
Recombinant Rabbit monoclonal primary
Recombinant L1CAM Monoclonal Antibody (ET1703-51)
Hela, human brain, human kidney tissue, human thyroid tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Neural cell adhesion molecule L1
N-CAM-L1, NCAM-L1, L1CAM
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Colocalized with SHTN1 in close apposition with actin filaments in filopodia and lamellipodia of axonalne growth cones of hippocampal neurons (By similarity). In neurons, detected predominantly in axons and cell body, weak localization to dendrites.
Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.