Lane 1: 293
Lane 2: NCCIT
Recombinant Rabbit monoclonal primary
Recombinant KLF4 Monoclonal Antibody (ET1702-71)
293, NCCIT, 293T, PC-3M, Hela, human liver tissue, mouse liver tissue, human gastric carcinoma tissue, mouse colon tissue, mouse stomach tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Krueppel-like factor 4
Belongs to the krueppel C2H2-type zinc-finger protein family.
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.