Recombinant Rabbit monoclonal primary
Recombinant Insulin Receptor R Monoclonal Antibody (ET1705-22)
Human colon cancer tissue, human kidney tissue, human liver cancer tissue, mouse testis tissue, mouse kidney tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Insulin Receptor R
INSRR antibody; INSRR_HUMAN antibody; Insulin receptor related receptor precursor antibody; Insulin receptor-related protein alpha chain antibody; Insulin receptor-related protein beta chain antibody; insulin receptor-related receptor antibody; IR R antibody; IR related receptor antibody; IR-related receptor antibody; IRR antibody; Sir r antibody; Sirr antibody
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Autophosphorylated on tyrosine residues between pH 7.9 and pH 10.5.
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment.Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.